Product Description

PICALM Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65700-50, BS65700-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regμlating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscμlar junction. A chromosomal translocation t(10, 11)(p13, q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Mμltiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Zebrafish, Sheep

Host: Rabbit

Applications: IHC-P

Alternate Names: CALM, Clathrin assembly lymphoid myeloid leukemia, Clathrin assembly lymphoid myeloid leukemia protein, CLTH, LAP, Phosphatidylinositol-binding clathrin assembly protein, PICAL_HUMAN, PICALM.  

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human PICALM/CALM:251-350/652 

Dilution: IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: PICALM Polyclonal Antibody detects endogenous levels of PICALM protein.

Molecular Weight: 71kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q13492

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only