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PIEZO2 Polyclonal Antibody - E-AB-17942

PIEZO2 Polyclonal Antibody - E-AB-17942

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PIEZO2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-17942-60, E-AB-17942-120, E-AB-17942-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PIEZO2

Target Synonym: Family with sequence similarity 38 member B; FLJ23144; FLJ23403; HsT748; Hypothetical protein LOC63895 ; PIEZ2; Piezo-type mechanosensitive ion channel component 2; Piezo2; Protein FAM38B

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9H5I5

Background: The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Concentration: 1.62 mg/mL

Immunogen: Synthetic peptide of human PIEZO2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only