Product Description

PIGW Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61315-50, BS61315-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Phosphatidylinositol-glycans (PIGs) are mμlti-pass transmembrane proteins that localize to the endoplasmic reticμlum. PIGs exhibit various functions, but all are crucial for the biosynthesis of the glycosylphosphatidylinositol (GPI)-anchor. Some PIG proteins are components of the GPI transamidase complex and play a role in the recognition of either the GPI attachment signal or the lipid portion of GPI. Other PIGs belong to the glycosyltransferase complex and function in the transfer of N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI). A variety of other PIGs play distinct roles in GPI synthesis including mannosylation of the GPI-anchor. PIG-W (Phosphatidylinositol-glycan biosynthesis class W protein) is a 504 amino acid mμlti-pass membrane protein that functions in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Phosphatidylinositol-glycan biosynthesis class W protein (EC:2.3.-.-), PIG-W, PIGW

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human PIGW.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PIGW polyclonal antibody detects endogenous levels of PIGW protein.

Molecular Weight: ~ 57 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -24°C long term. Avoid freeze-thaw cycles.

SwissProt: Q7Z7B1

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only