Product Description

PIK3C2G Polyclonal Antibody

Catalogue Numbers: BS60313-50, BS60313-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O75747

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Phosphoinositide 3-kinase activity is implicated in assorted cellular responses activated by mammalian cell surface receptors and the regulation of protein sorting in yeast. The p110γ (PIK3CG) enzyme is activated in vitro by both the α and βγ subunits of heterotrimeric GTP-binding proteins (G proteins) and does not associate with a p85 adaptor molecule. PI 3-kinase C2γ, also designated p110γ, may link signaling through G protein-coupled receptors to the generation of phosphoinositide second messengers that are phosphorylated in the D-3 position. The PI 3-kinase C2γ gene encodes a 1,050 amino acid polypeptide with 36% identity to human PI 3-kinase C2α. Research indicates that PI 3-kinase C2γ can block the growth of human colon cancer cells.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PIK3C2G polyclonal antibody detects endogenous levels of PIK3C2G protein.

Extra Notes: Western blot (WB) analysis of PIK3C2G polyclonal antibody at 1:500 dilution
Lane1:PC3 whole cell lysate(40µg)
Lane2:HepG2 whole cell lysate(40µg)

Bioworld Molecular Weight: ~ 171 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; PI3K-C2-gamma; Short name=PtdIns-3-kinase C2 subunit gamma; Phosphoinositide 3-kinase-C2-gamma; PI 3-kinase C2γ; PI3KC2γ

Immunogen: A synthetic peptide corresponding to residues in Human PIK3C2G.

Conjugate: Unconjugated

Modification: Unmodified