Product Description

PIP5K (Q95) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2676-50, BS2676-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4, 5-bisphosphate, which regμlates various processes including cell proliferation, survival, membrane trafficking and cytoskeletal organization. The PIPK family is divided into type I, type II and type III. Each type of the PIPK family phosphorylates distinct substrates. They contain an activation loop, which determines their enzymatic specificity and subcellμlar targeting. The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I α, β and γ, which are characterized by phosphorylating PI4P on the 5-hydroxyl. PIPK I α, designated PIPK I β in mouse, is expressed in brain tissue. PIPK I β, designated PIPK I α in mouse, is also called STM7. PIPK I γ has two variants produced by alternative splicing which are expressed in lung, brain and kidneys.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: 1-phosphatidylinositol 3-phosphate 5-kinase, Phosphatidylinositol 3-phosphate 5-kinase, FYVE finger-containing phosphoinositide kinase, PIKfyve, Phosphatidylinositol 3-phosphate 5-kinase type III, PIPkin-III, Type III PIP kinase, PIKFYVE, KIAA0981, PIP5K3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 65-125 of Human PIP5K.

Dilution: WB: 1:1000~1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PIP5K (Q95) Polyclonal Antibody detects endogenous levels of PIP5K protein.

Molecular Weight: ~ 237 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9Y2I7

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only