Product Description

PKC gamma (Phospho-T514) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS64581-50, BS64581-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Members of the protein kinase C (PKC) family play a key regμlatory role in a variety of cellμlar functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into many different isoforms (α, βI, βII, γ, δ, ε, ζ, η, λ, ν, μ, ι, and θ).

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB

Alternate Names: Protein kinase C gamma type, PKC-gamma, PKCG, PRKCG

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: Synthetic phosphopeptide derived from human PKC gamma around the phosphorylation site of Threonine 514.

Dilution: WB:1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PKC gamma (Phospho-T514) polyclonal antibody detects endogenous levels of PKC gamma protein only when phosphorylated at Thr514.

Molecular Weight: ~ 80 kDa

Pathway: Protein Kinase C Signaling,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P05129

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only