PKD1 (phospho Tyr463) rabbit pAb - ES6787

PKD1 (phospho Tyr463) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6787-50, ES6787-100

Citations, Manuals and MSDS Available upon request.

Background: PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009 [PubMed 19329994]).[supplied by OMIM, Nov 2010],

Alternate Name: PRKD1; PKD; PKD1; PRKCM; Serine/threonine-protein kinase D1; Protein kinase C mu type; Protein kinase D; nPKC-D1; nPKC-mu

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human PKD1/PKC mu around the phosphorylation site of Tyr463. AA range:429-478

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 130kD

Human Gene ID: 5587

Human SWISS Prot NO: Q15139

Subcellular Location: Cytoplasm. Cell membrane. Golgi apparatus trans-Golgi network. Translocation to the cell membrane is required for kinase activation.

Research Use Only