PKD1 Polyclonal Antibody - E-AB-15660

PKD1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-15660-60, E-AB-15660-120, E-AB-15660-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PKD1

Target Synonym: Autosomal dominant polycystic kidney disease 1 protein; Autosomal dominant polycystic kidney disease protein 1; nPKC-D1; nPKC-mu; OTTHUMP00000208669; OTTHUMP00000208670; PBP; Pc-1; PKD; Pkd1; PKD1; Polycystic Kidney Disease 1; polycystic kidney disease-associated protein; Polycystin 1 Precursor; Polycystin-1; Protein kinase C mu type; Protein kinase D; Serine/threonine-protein kinase D1; transient receptor potential cation channel; subfamily P; member 1; TRPP1

Research Areas: Cancer, Metabolism, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P98161

Background: This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1).

Concentration: 0.6 mg/mL

Immunogen: Synthetic peptide of human PKD1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only