Product Description

PKN3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34122-50, RA34122-100

Citations, Manuals and MSDS Available upon request.

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The C1 domain does not bind the diacylglycerol (DAG) .,enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation.,function:Contributes to invasiveness in malignant prostate cancer.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 REM (Hr1) repeats.,subcellular location:Nuclear and perinuclear Golgi region.,tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.,

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 29941

Protein MW (KDa): 97

SWISS: Q6P5Z2

Source: Rabbit

Research Use Only