Product Description

PKR/EIF2AK2 Polyclonal Antibody

Sizes: 50 µl, 100 µl

Catalogue Numbers: BS71944-50, BS71944-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P19525

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF/ICC

All Applications: WB,1:500 - 1:2000 | IHC,1:100 - 1:200 | IF/ICC,1:50 - 1:200

Background: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Polyclonal Antibodies

Bioworld Molecular Weight: 74kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: EIF2AK1; PKR; PPP1R83; PRKR; Eif2ak2; EIF2AK2

Immunogen: Recombinant fusion protein of human PKR/PKR/EIF2AK2(NP_002750.1).

Conjugate: Unconjugated

Modification: Unmodified