Plakophilin 2 rabbit pAb - ES3232

Plakophilin 2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3232-50, ES3232-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008],

Alternate Name: PKP2; Plakophilin-2

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human PKP2. AA range:632-681

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 97kD

Human Gene ID: 5318

Human SWISS Prot NO: Q99959

Subcellular Location: Nucleus. Cell junction, desmosome. Nuclear and associated with desmosomes.

Research Use Only