Plasminogen rabbit pAb - ES6617

Plasminogen rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6617-50, ES6617-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009],

Alternate Name: PLG; Plasminogen

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from the Internal region of human Plasminogen.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 90kD

Human Gene ID: 5340

Human SWISS Prot NO: P00747

Subcellular Location: Secreted. Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface.

Research Use Only