PLC gamma2 (Phospho-Tyr759) Rabbit Polyclonal Antibody - BT-AP11995

PLC gamma2 (Phospho-Tyr759) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11995-20, BT-AP11995-50, BT-AP11995-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4|5-bisphosphate to 1D-myo-inositol 1|4|5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation| antibody deficiency| and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

Research Areas: Cardiovascular; Metabolism; Signal transduction

Target Protein: PLCG2

Applications: WB

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: PLCγ2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P16885; Mouse: Q8CIH5; Rat: P24135

Synonyms: PLCγ2;Tyr759; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase gamma-2; EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-IV; PLC-IV; Phospholipase C-gamma-2; PLC-gamma-2

GeneID: Human: 5336; Mouse: 234779; Rat: 29337

Research Use Only