PLCD1 Polyclonal Antibody - BT-AP13167

PLCD1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13167-20, BT-AP13167-50, BT-AP13167-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Areas: Signal transduction

Target Protein: PLCD1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P51178; Mouse: Q8R3B1; Rat: P10688

Synonyms: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1;EC 3.1.4.11;Phosphoinositide phospholipase C-delta-1;Phospholipase C-III;PLC-III;Phospholipase C-delta-1;PLC-delta-1

GeneID: Human: 5333

Research Use Only