PLCD3 rabbit pAb - ES14071

PLCD3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES14071-50, ES14071-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to generate the second messengers diacylglycerol and inositol 1, 4, 5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca (2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human PLCD3 AA range: 501-551

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 113026

Human SWISS Prot NO: Q8N3E9

Subcellular Location: Membrane; Peripheral membrane protein. Cytoplasm. Cleavage furrow. Localizes at the cleavage furrow during cytokinesis.

Research Use Only