Product Description

PLEKHO1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65753-50, BS65753-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Plays a role in the regμlation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2(CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regμlated muscle differentiation, the regμlation of AP-1 activity (plasma membrane bound AP-1 regμlator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: FCM

Alternate Names: PLEKHO1, C-Jun-binding protein, Casein kinase 2-interacting protein 1, CK2 interacting protein 1, CK2 interacting protein 1 HQ0024c protein, CK2-interacting protein 1, CKIP-1, CKIP 1, CKIP1, JBP, OC120, Osteoclast maturation associated gene 120 protein, Pleckstrin homology domain containing family O member 1, PKHO1_HUMAN.聽

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human PLEKHO1:51-170/409

Dilution: Flow-Cyt=1ug/test

Purification: affinity purified by Protein A

Specificity: PLEKHO1 Polyclonal Antibody detects endogenous levels of PLEKHO1 protein.

Molecular Weight: 45kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q53GL0

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only