BT Lab
Plk Polyclonal Antibody - BT-AP07277
Plk Polyclonal Antibody - BT-AP07277
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Plk Polyclonal Antibody
Sizes: 20μL, 50μL, 100μL
Catalogue Numbers: BT-AP07277-20, BT-AP07277-50, BT-AP07277-100
Citations, Manuals and MSDS Available upon request.
Background: The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.
Research Areas: Cell Biology
Target Protein: PLK1
Applications: WB, IHC-p, IF, ELISA
Reactivity: Human, Mouse, Rat
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Full Product Name: Plk Antibody
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage: -20°C for 1 year
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Molecular Weight (Da): 68255
UniProt Accession: Human: P53350; Mouse: Q07832; Rat: Q62673
Synonyms: PLK1; PLK; Serine/threonine-protein kinase PLK1; Polo-like kinase 1; PLK-1; Serine/threonine-protein kinase 13; STPK13
GeneID: Human: 5347; Mouse: 18817; Rat: 25515
Research Use Only
