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PLK1 Monoclonal Antibody - MB11434

PLK1 Monoclonal Antibody - MB11434

Regular price $424.50 CAD
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PLK1 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB11434-50, MB11434-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regμlating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regμlation of AURKA function. Regμlates TP53 stability through phosphorylation of TOPORS.

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB, ICC/IF, IP

Alternate Names: PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, STPK13

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthetic peptide of human PLK1

Dilution: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 68 kDa, Observed MW: 68 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P53350

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Research Use Only

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