PLOD1 rabbit pAb - ES14063

PLOD1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES14063-50, ES14063-100

Citations, Manuals and MSDS Available upon request.

Background: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human PLOD1 AA range: 551-601

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 5351

Human SWISS Prot NO: Q02809

Subcellular Location: Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.

Research Use Only