PLSCR3 Monoclonal Antibody-MB11435

PLSCR3 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11435-50, MB11435-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9NRY6

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,

All Applications: WB: 1/500-1/1000

Background: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 32 kDa; Observed MW: 32 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PLSCR3 in rat lung, mouse lung lysates using PLSCR3 antibody., Western blot analysis of PLSCR3 in K562, Hela lysates using PLSCR3 antibody.

Alternative Name: Phospholipid scramblase 3; PL scramblase 3

Immunogen: A synthetic peptide of human PLSCR3

Conjugate: Unconjugated

Modification: Unmodified