Product Description

PLXNA4 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60789-50, BS60789-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Plexin-A4, also known as PLXNA4 or FAYV2820, is a 1, 894 amino acid singlepass type I membrane protein that contains one sema domain, three PSI domains and four IPT/TIG domains. Belonging to a large family of semaphorin (SEMA) receptors, plexin-A4 forms a complex with neuropilin and, once complexed, can propagate SEMA3A-induced inhibitory signals into neurons and cells, possibly playing a role in early nerve development. Four isoforms of plexin-A4 exist due to alternative splicing events. The gene encoding plexin-A4 maps to human chromosome 7, which houses over 1, 000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, lissencephaly, citrμllinemia and Shwachman-Diamond syndrome.

Category: Primary Antibody

Reactivity: Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Plexin-A4, PLXNA4, KIAA1550, PLXNA4A, PLXNA4B, UNQ2820, PRO34003

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human PLXNA4.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PLXNA4 polyclonal antibody detects endogenous levels of PLXNA4 protein.

Molecular Weight: ~ 212 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9HCM2

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only