Product Description

PMVK Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65912-50, BS65912-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: PMVK is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart, liver, skeletal muscle, kidney, and pancreas with lower expression in brain, placenta and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway. PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, which houses over 3, 000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep

Host: Rabbit

Applications: WB

Alternate Names: hPMK, HUMPMKI, Phosphomevalonate kinase, PMK, PMK PEN, PMKA, PMKase, PMKI, PMKPEN, PMVK, PMVK_HUMAN, EC 2.7.4.2.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human PMVK:15-120/192

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: PMVK Polyclonal Antibody detects endogenous levels of PMVK protein.

Molecular Weight: 24 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15126

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only