PNK1 (phospho-Ser114/Thr118) rabbit pAb - ES14048

PNK1 (phospho-Ser114/Thr118) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES14048-50, ES14048-100

Citations, Manuals and MSDS Available upon request.

Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010],

Alternate Name: Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2' (3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)]

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized phosho peptide around human PNK1 (Ser114 and Thr118)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 57kD

Human Gene ID: 11284

Human SWISS Prot NO: Q96T60

Subcellular Location: Nucleus. Chromosome. Localizes to site of double-strand breaks.

Research Use Only