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PNK1 (Phospho-Ser114/Thr118) Rabbit Polyclonal Antibody - BT-AP12042

PNK1 (Phospho-Ser114/Thr118) Rabbit Polyclonal Antibody - BT-AP12042

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PNK1 (Phospho-Ser114/Thr118) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12042-20, BT-AP12042-50, BT-AP12042-100

Citations, Manuals and MSDS Available upon request.

Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage| the protein encoded by this locus catalyzes 5andapos; phosphorylation and 3andapos; dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly| seizures| and developmental delay.

Research Areas: Epigenetics and nuclear signaling

Target Protein: PNKP

Applications: WB

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: PNK1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q96T60; Mouse: Q9JLV6

Synonyms: PNK1;Ser114/Thr118; Bifunctional polynucleotide phosphatase/kinase; DNA 5'-kinase/3'-phosphatase; Polynucleotide kinase-3'-phosphatase [Includes: Polynucleotide 3'-phosphatase; EC 3.1.3.32; 2';3'-polynucleotidase; Polynucleotide 5'-hydroxyl-kinase; EC 2.7.1.78;

GeneID: Human: 11284

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