PNKP Polyclonal Antibody - BT-AP13205

PNKP Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13205-20, BT-AP13205-50, BT-AP13205-100

Citations, Manuals and MSDS Available upon request.

Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5andapos; phosphorylation and 3andapos; dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Research Areas: Epigenetics and nuclear signaling

Target Protein: PNKP

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Bifunctional polynucleotide phosphatase/kinase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q96T60; Mouse: Q9JLV6

Synonyms: Bifunctional polynucleotide phosphatase/kinase;DNA 5'-kinase/3'-phosphatase;Polynucleotide kinase-3'-phosphatase [Includes: Polynucleotide 3'-phosphatase;EC 3.1.3.32;2';3'-polynucleotidase; P

GeneID: Human: 11284

Research Use Only