Product Description

PNPLA6 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61695-50, BS61695-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Neuropathy target esterase (NTE) is a member of a newly discovered protein family, with a domain conserved through evolution. It is an integral membrane protein present in all neurons and in some non-neural cell types of vertebrates. NTE is important in neural development and has the capacity to hydrolyse esters. It is important in the cell-signalling pathway controlling interactions between neurons and accessory glial cells in nervous system development. NTE can be modified by organophosphates, which can cause neuropathy (characterized by axonal degeneration) in humans. NTE loss can lead to prominent neuronal pathology in the thalamus amd hippocampus and can also lead to defects in the cerebellum.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Neuropathy target esterase, Patatin-like phospholipase domain-containing protein 6, PNPLA6, NTE

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding Human PNPLA6.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PNPLA6 polyclonal antibody detects endogenous levels of PNPLA6 protein.

Molecular Weight: ~ 150 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8IY17

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only