PNPO Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-19759-60, E-AB-19759-120, E-AB-19759-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PNPO
Target Synonym: EC 1.4.3.5; FLJ10535; PDXPO; PNPO; PNPO; Pyridoxal 5' phosphate synthase; pyridoxamine 5' phosphate oxidase; Pyridoxamine phosphate oxidase ; Pyridoxamine-phosphate oxidase; pyridoxine 5' phosphate oxidase; Pyridoxine-5'-phosphate oxidase
Research Areas: Metabolism, Neuroscience, Signal transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9NVS9
Background: The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.
Concentration: 0.9 mg/mL
Immunogen: Synthetic peptide of human PNPO
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000
Calculated MW: 30 kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only