POLD4 Rabbit pAb
Sizes: 50μL, 100μL
Catalogue Numbers: ES14032-50, ES14032-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],
Alternate Name: DNA polymerase delta subunit 4 (DNA polymerase delta subunit p12)
Source: Rabbit
Applications: WB; IHC; IF; ELISA
Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Reactivity: Human; Rat; Mouse;
Immunogen: Synthesized peptide derived from human POLD4 AA range: 43-93
Storage and Stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human Gene ID: 57804
Human SWISS Prot NO: Q9HCU8
Subcellular Location: Nucleus. Partially recruited to DNA damage sites within 2 hours following UV irradiation, before degradation.
Research Use Only