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POLG2 Polyclonal Antibody - E-AB-61303

POLG2 Polyclonal Antibody - E-AB-61303

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POLG2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-61303-60, E-AB-61303-120, E-AB-61303-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: POLG2

Target Synonym: POLG2; HP55; MTPOLB; PEOA4; POLB; POLG-BETA; POLGB

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9UHN1

Background: This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human POLG2 (NP_009146.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200 IF 1:10-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only