POLR2E Polyclonal Antibody - BT-AP07318

POLR2E Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07318-20, BT-AP07318-50, BT-AP07318-100

Citations, Manuals and MSDS Available upon request.

Background: POLR2E (RNA polymerase II subunit E) encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for POLR2E.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: POLR2E

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: POLR2E Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 24551

UniProt Accession: Human: P19388; Mouse: Q80UW8; Rat: B0BNE2

Synonyms: POLR2E; DNA-directed RNA polymerases I; II, and III subunit RPABC1; RNA polymerases I, II, and III subunit ABC1; DNA-directed RNA polymerase II 23 kDa polypeptide; DNA-directed RNA polymerase II subu

GeneID: Human: 5434; Mouse: 66420; Rat: 690966

Research Use Only