Product Description

POLR2I Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60145-50, BS60145-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: RNA polymerase II (Pol II) is a mμlti-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits. This complex interacts with the promoter regions of genes and a variety of elements and transcription factors. POLR2I (polymerase (RNA) II (DNA directed) polypeptide I), also known as RPB9 or hRPB14.5, is a 125 amino acid nuclear protein belonging to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. Component of RNA polymerase II, POLR2I catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR2I is part of the upper jaw surrounding the central large cleft and is thought to grab the incoming DNA template.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: DNA-directed RNA polymerase II subunit RPB9, RNA polymerase II subunit B9, DNA-directed RNA polymerase II subunit I, RNA polymerase II 14.5 kDa subunit, RPB14.5

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human POLR2I.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: POLR2I polyclonal antibody detects endogenous levels of POLR2I protein.

Molecular Weight: ~ 14 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P36954

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only