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Polyclonal AntibodyPC1 Polyclonal Antibody - E-AB-65139

Polyclonal AntibodyPC1 Polyclonal Antibody - E-AB-65139

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Polyclonal AntibodyPC1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-65139-60, E-AB-65139-120, E-AB-65139-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: Rabbit pAbPC1

Target Synonym: PABPC1; PAB1; PABP; PABP1; PABPC2; PABPL1

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P11940

Background: This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human PABPC1 (NP_002559.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:100 IF 1:50-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only