POT1 Polyclonal Antibody - BT-AP07334

POT1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07334-20, BT-AP07334-50, BT-AP07334-100

Citations, Manuals and MSDS Available upon request.

Background: POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: POT1

Applications: WB, ELISA

Reactivity: Human, Monkey

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: POT1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 71442

UniProt Accession: Human: Q9NUX5; Mouse: Q91WC1

Synonyms: POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein

GeneID: Human: 25913

Research Use Only