Product Description

POT1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28931-50, RA28931-100

Citations, Manuals and MSDS Available upon request.

Background: protection of telomeres 1 (POT1) Homo sapiens This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein

Applications: WB; ELISA

Species Cross-Reactivity: Human; Monkey

GeneID (Human): 25913

Protein MW (KDa): 70

SWISS: Q9NUX5

Source: Rabbit

Research Use Only