PP2B-Aα Rabbit Polyclonal Antibody - RA28946

PP2B-Aα Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28946-50, RA28946-100

Citations, Manuals and MSDS Available upon request.

Background: catalytic activity:A phosphoprotein + H (2) O = a protein + phosphate.,cofactor:Binds 1 Fe (3+) ion per subunit.,cofactor:Binds 1 zinc ion per subunit.,function:Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1 and SSH1.,online information:Calcineurin entry,similarity:Belongs to the PPP phosphatase family.,similarity:Belongs to the PPP phosphatase family. PP-2B subfamily.,subcellular location:Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle.,subunit:Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with TORC2/CRTC2, MYOZ1, MYOZ2 and MYOZ3.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000

Alternative Names: Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform (EC 3.1.3.16;CAM-PRP catalytic subunit;Calmodulin-dependent calcineurin A subunit alpha isoform)

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5530

SWISS: Q08209

Source: Rabbit

Research Use Only