PPAR α (Phospho Ser21) rabbit pAb - ES20158

PPAR α (Phospho Ser21) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20158-50, ES20158-100

Citations, Manuals and MSDS Available upon request.

Background: function:Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids., online information:Peroxisome proliferator-activated receptor entry, similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily., similarity:Contains 1 nuclear receptor DNA-binding domain., subunit:Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13., tissue specificity:Skeletal muscle, liver, heart and kidney.,

Alternate Name: Peroxisome proliferator-activated receptor alpha (PPAR-alpha; Nuclear receptor subfamily 1 group C member 1)

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human PPAR α (Phospho Ser21)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 52kD

Human Gene ID: 5465

Human SWISS Prot NO: Q07869

Subcellular Location: Nucleus

Research Use Only