PPAR α (Phospho Ser21) Rabbit Polyclonal Antibody - RA28952

PPAR α (Phospho Ser21) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28952-50, RA28952-100

Citations, Manuals and MSDS Available upon request.

Background: function:Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.,online information:Peroxisome proliferator-activated receptor entry,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13.,tissue specificity:Skeletal muscle, liver, heart and kidney.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000

Alternative Names: Peroxisome proliferator-activated receptor alpha (PPAR-alpha;Nuclear receptor subfamily 1 group C member 1)

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 5465

Protein MW (KDa): 52

SWISS: Q07869

Source: Rabbit

Research Use Only