PPAR-α rabbit pAb - ES6666

PPAR-α rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6666-50, ES6666-100

Citations, Manuals and MSDS Available upon request.

Background: peroxisome proliferator activated receptor alpha (PPARA) Homo sapiens Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for thi

Alternate Name: PPARA; NR1C1; PPAR; Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human PPAR-alpha. AA range:6-55

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 52kD

Human Gene ID: 5465

Human SWISS Prot NO: Q07869

Subcellular Location: Nucleus

Research Use Only