Product Description

PPAR Delta Mouse Monoclonal Antibody (1D7)

Sizes: 50μL, 100μL

Catalogue Numbers: RA11873-50, RA11873-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: peroxisome proliferator activated receptor delta (PPARD) Homo sapiens This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this

Reactivity: Human, Rat, Mouse

Host: Mouse

Applications: IHC-p, IF(paraffin section)

Alternate Names: Peroxisome proliferator-activated receptor delta (PPAR-delta, NUCI, Nuclear hormone receptor 1, NUC1, Nuclear receptor subfamily 1 group C member 2, Peroxisome proliferator-activated receptor beta, PPAR-beta)

Clonality: Monoclonal

Dilution: IHC 1:100-200

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 5467

Protein Molecular Weight（KDa): 50

Molecular Weight: 50

Research Use Only