PPARA Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A24835-20, A24835-100
Citations, Manuals and MSDS Available upon request.
Background: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.
Category: Polyclonal Antibodies
Applications: WB
Cross-reactivity: Mouse
Protein Weight: 52kDa
Observed Molecular Weight: 52kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 5465
SWISS: Q07869
Alternate Names: PPAR; NR1C1; hPPAR; PPARalpha; PPARA
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000
Research Areas: Epigenetics & Nuclear Signaling, Transcription Factors, Nuclear Receptor Signaling, Nuclear hormone receptors, Cancer, Signal Transduction, Endocrine & Metabolism, Mitochondrial metabolism, Mitochondrial Biogenesis, Lipid Metabolism, Nucleotide metabolism, Molecular processes, Cardiovascular, Hypoxia, Lipids, Fatty Acids.
NCBI Alias: PPARA
Research Use Only