PPARGC1B Monoclonal Antibody - BT-MCA2705

PPARGC1B Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2705-50, BT-MCA2705-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cardiovascular, Epigenetics and nuclear signaling, Metabolism, Signal transduction

Target Protein: PPARGC1B

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1C1C2

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: PPARGC1B

Immunogen: Purified recombinant fragment of human PPARGC1B (AA: 195-414) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Molecular Weight (Da): 113.2kDa

UniProt Accession: Q86YN6

Synonyms: PERC, ERRL1, PGC1B, PGC-1(beta)

GeneID: 133522

Research Use Only