PPGB (20k, Cleaved-Met327) rabbit pAb - ES20021

PPGB (20k, Cleaved-Met327) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20021-50, ES20021-100

Citations, Manuals and MSDS Available upon request.

Background: catalytic activity:Release of a C-terminal amino acid with broad specificity., disease:Defects in CTSA are the cause of galactosialidosis [MIM:256540]. It is an autosomal recessive disease., function:Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins., similarity:Belongs to the peptidase S10 family., subunit:Heterodimer of a 32 kDa chain and a 20 kDa chain; disulfide-linked.,

Alternate Name: Lysosomal protective protein (EC 3.4.16.5; Carboxypeptidase C; Carboxypeptidase L; Cathepsin A; Protective protein cathepsin A; PPCA; Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain]

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human PPGB (20k, Cleaved-Met327)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 20 52kD

Human Gene ID: 5476

Human SWISS Prot NO: P10619

Subcellular Location: Lysosome.

Research Use Only