PPM1F Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-16729-60, E-AB-16729-120, E-AB-16729-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PPM1F
Target Synonym: Ca(2+)/calmodulin-dependent protein kinase phosphatase; CaM-kinase phosphatase; CAMKP; CaMKPase; FEM 2; hFEM-2; KIAA0015; Partner of PIX 2; POPX2; PP2C phosphatase; Ppm1f; PPM1F; Protein fem-2 homolog; Protein phosphatase 1F (PP2C domain containing); Protein phosphatase 1F; Protein phosphatase Mg2+/Mn2+ dependent 1F
Research Areas: Cell biology, Signal transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P49593
Background: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase.
Concentration: 0.8 mg/mL
Immunogen: Synthetic peptide of human PPM1F
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Calculated MW: 50kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only