PPP1R1A Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-18912-60, E-AB-18912-120, E-AB-18912-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PPP1R1A
Target Synonym: I 1; I-1; I1; Inhibitor 1; IPP 1; IPP-1; IPP1; Ppp1r1a; PPR1A; Protein phosphatase 1 regulatory (inhibitor) subunit 1A; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase inhibitor 1
Research Areas: Cancer, Metabolism, Signal transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q13522
Background: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
Concentration: 1.02 mg/mL
Immunogen: Fusion protein of human PPP1R1A
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only