Product Description

PPP4C Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10295-50, MB10295-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P60510

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PPX in K562, C6, 3T3, HelaLysates using PPP4C antibody.

Bioworld Molecular Weight: Calculated MW: 35 kDa; Observed MW: 35 kDa

Specificity: IgG

Alternative Name: PP4; PPX; PP4C; PPH3; PPP4

Immunogen: Recombinant protein of human PPP4C

Conjugate: Unconjugated

Modification: Unmodified