PRAK Monoclonal Antibody - RA11887

PRAK Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11887-50, RA11887-100

Citations, Manuals and MSDS Available upon request.

Background: mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5) Homo sapiens The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 8550

SWISS: Q8IW41

Source: Mouse

Research Use Only