PRAS40 (phospho Thr246) rabbit pAb - ES7749

PRAS40 (phospho Thr246) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7749-50, ES7749-100

Citations, Manuals and MSDS Available upon request.

Background: AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008],

Alternate Name: AKT1S1; PRAS40; Proline-rich AKT1 substrate 1; 40 kDa proline-rich AKT substrate

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Akt1 S1 around the phosphorylation site of Thr246. AA range:207-256

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 40kD

Human Gene ID: 84335

Human SWISS Prot NO: Q96B36

Subcellular Location: Cytoplasm, cytosol. Found in the cytosolic fraction of the brain.

Research Use Only