PRDM12 Polyclonal Antibody - E-AB-91897

PRDM12 Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-91897-60, E-AB-91897-120, E-AB-91897-200 Citations, Manuals and MSDS Available upon request. Abbreviation: PRDM12 Target Synonym: HSAN8; PFM9; PRDM12 Research Areas: Epigenetics and Nuclear Signaling Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human, Mouse Application: WB Isotype: IgG Clonality: Polyclonal UNIProt ID: Q9H4Q4 Background: This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia. [provided by RefSeq, Mar 2017] Concentration: 1mg/mL Immunogen: Recombinant fusion protein of human PRDM12 Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3. Purification Method: Affinity purification Dilution: WB 1:500-1:2000 Observed MW: 45kDa Storage: -20°C/One year. Avoid freeze / thaw cycles. Shipping: Ice bag Research Use Only