PRDM3 rabbit pAb - ES6215

PRDM3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6215-50, ES6215-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],

Alternate Name: MECOM; MDS1; MDS1 and EVI1 complex locus protein MDS1; Myelodysplasia syndrome 1 protein; Myelodysplasia syndrome-associated protein 1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human MECOM. AA range:1-50

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 18kD

Human Gene ID: 4197

Human SWISS Prot NO: Q13465

Subcellular Location: histone deacetylase complex, nucleus, nucleoplasm, cytoplasm, Golgi apparatuscytosol, aggresome, nuclear speck, intracellular membrane-bounded organelle,

Research Use Only