Product Description

PRDM6 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS70954-50, BS70954-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9NQX0

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB 1:500 - 1:2000

Background: PRDM6 is a zinc-finger domain containing protein that belongs to a family of PRDM (PRDI-BF1 and RIZ homology domain) proteins that act as agents for chromatin remodeling. The PRDM family is often associated with gene regulation and chromatin remodeling by way of their histone methyltransferase abilities. PRDM6 can function as a transcriptional repressor through interactions with the deacetylases and methyltransferases associated with Histone H4. PRDM6 is expressed in vascular precursor cells and likely has a role in development and differentiation of vascular tissue through its ability to remodel chromatin.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PRDM6 polyclonal antibody detects endogenous levels of PRDM6 protein.

Bioworld Molecular Weight: ~ 80 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of various cells, using PRDM6 antibody.

Alternative Name: PFM3

Immunogen: Recombinant protein of human PRDM6.

Conjugate: Unconjugated

Modification: Unmodified